It consists of a genetic test performed before implantation of embryos, and a breakthrough science of human reproduction that brings tranquility for couples who, for various reasons, need to ensure the quality of the embryos to be implanted in the womb.
For whom is PGD indicated?
PGD is indicated for:
- Women at advanced age (over 37 years old);
- Men with low quality sperm;
- Couples who have children with chromosomal disorder;
- Couples with chromosomal disorder;
- Couples with genetic disease history;
- Couples who have been diagnoses as having altered pregnancy during pre-natal exams;
- Couples with recurrent IVF failure;
- Couples with recurrent abortion history;
- Couples with idiopatic infertility (without apparent cause).
How is PGD done?
PGD can be performed only after assisted reproduction cycle, which consists of the collection and subsequent fertilization of the oocyte by sperm outside the woman’s body. With PGD, a cell is removed from the embryo using microsurgical techniques and this cell is attached to a microscope slide.
Specialized cytogeneticists analyze the cell using a technique called FISH (fluorescent in situ hybridization). Meanwhile, the embryo remains in an incubator without risk to their development until the day of transfer to the womb, after the outcome of PGD.